WEIGHT LOSS PILL TYPE: An Appetite suppressant and central nervous system stimulant; formerly part of the combination product fen-phen, phentermine was approved for weight management by the FDA in 1973. It is a Schedule IV controlled substance, with low potential for abuse.
SOLD AS: phentermine is available in 15-mg and 30-mg capsules, and also as phentermine hydrochloride in 37.5-mg. capsules, comparable to 30 mg of phentermine base.
RESEARCH: The majority of the publicized reports on phentermine incorporate its use in in conjunction with fenfluramine. Among the several scientific studies in which its usefulness alone was examined, it was discovered that the drug resulted in an average weight loss of 14 pounds after 20 weeks of treatment.
The most significant concern about using the combination product fen-phen was the increased risk of heart-valve abnormalities. In the May 2000 issue of Circulation, scientists documented the outcomes of their substantial analysis into this issue, praoclaiming that findings suggest that valvular abnormalities in patients who took fenfluramine-phentermine mainly include those who had taken these medicines for more than 6 months and primarily results in mild aortic regurgitation. This research did not demonstrate the use of phentermine alone to be associated with cardiovascular disease.
WHAT IS IT SUPPOSED TO DO: Phentermine stimulates the satiety (feeling of fullness) center in the hypothalamus and limbic parts of the brain, where appetite and hunger are managed. In order to work, phentermine should be used in addition to a sensible eating plan, behavior modification, and a physical fitness program. Nevertheless, weight loss may be short-term only, particularly after the drug is ended. To keep up weight loss or to continue to lose more weight after stopping phentermine, it is crucial to adhere to a sensible eating plan and an exercise program.
HOW TO TAKE IT: phentermine can be taken in a number of ways, according to your lifestyle. One 30-mg capsule decreases appetite for about 12 to 14 hours. (1) Take 1 capsule 30 minutes before breakfast on an empty stomach. Do not take late in the day, as it can make it difficult to fall asleep or stay asleep. (2) Take 1 capsule about 2 hours after breakfast. phentermine is only approved for use for 12 weeks, after which some users reach drug tolerance and weight loss ceases.
SIDE EFFECTS: The most typical side effects include dry mouth; nausea; sleeplessness; headache; stomach upset; constipation; and irritability.
PRECAUTIONS: If you have any of the following medical conditions, tell your doctor before starting phentermine: high blood pressure, overactive thyroid, glaucoma, diabetes, or emotional problems. Limit alcohol use, as it can cause dizziness. Do not take phentermine if you are also taking an MAO inhibitor.
Phentermine, like other appetite suppressants, often causes dry mouth, which can increase the chance of developing gum disease and dental cavities. Special attention to oral hygiene, including use of sugarless gum and sugarless hard candies. Drinking lots of water, or sucking on ice chips, is recommended while taking these drugs.
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